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Article

Microglia subtypes show substrate- and time-dependent phagocytosis preferences and phenotype plasticity.

Frontiers in immunology - 1 Jan 2022

Li Shuailong, Wernersbach Isa, Harms Gregory S, Schäfer Michael K E

Abstract excerpt

Microglia are phagocytosis-competent CNS cells comprising a spectrum of subtypes with beneficial and/or detrimental functions in acute and chronic neurodegenerative disorders. The heterogeneity of microglia suggests differences in phagocytic activity and phenotype plasticity between microglia subtypes. To study these issues, primary murine glial cultures were cultivated in the presence of serum, different growth...

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Identifiers

PMID: 36105813
DOI: 10.3389/fimmu.2022.945485
PMCID: PMC9465456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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