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CRISPR/Cas9 gene editing: New hope for Alzheimer's disease therapeutics

6 Jul 2021

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is an insidious, irreversible, and progressive neurodegenerative health condition manifesting as cognitive deficits and amyloid beta (Aβ) plaques and neurofibrillary tangles. Approximately 50 million individuals are affected by AD, and the number is rapidly increasing globally. This review explores the role of CRISPR/Cas9 gene editing in the management of AD and its clinical...

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PMID: 36100328
DOI: 10.1016/j.jare.2021.07.001

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