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Article

Asian-specific 3'UTR variant in CDKN2B associated with risk of pituitary adenoma.

Molecular biology reports - 1 Nov 2022

Youn Byeong Ju, Cheong Hyun Sub, Namgoong Suhg, Kim Lyoung Hyo, Baek In Ki, Kim Jeong-Hyun, Yoon Seon-Jin, Kim Eui Hyun, Kim Se Hoon, Chang Jong Hee, Kim Sun Ho, Shin Hyoung Doo

Abstract excerpt

BACKGROUND: Previous genomewide association studies (GWASs), single nucleotide polymorphisms (SNPs) on cyclin-dependent kinase inhibitor 2 A (CDKN2A), cyclin-dependent kinase inhibitor 2B (CDKN2B), and cyclin-dependent kinase inhibitor 2B antisense RNA1 (CDKN2B-AS1) were reported as risk loci for glioma, a subgroup of the brain tumor. To further characterize this association with the risk of brain tumors in a...

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PMID: 36097105
DOI: 10.1007/s11033-022-07796-1

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