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Article

Spatial structure alters the site frequency spectrum produced by hitchhiking.

Genetics - 1 Nov 2022

Min Jiseon, Gupta Misha, Desai Michael M, Weissman Daniel B

Abstract excerpt

The reduction of genetic diversity due to genetic hitchhiking is widely used to find past selective sweeps from sequencing data, but very little is known about how spatial structure affects hitchhiking. We use mathematical modeling and simulations to find the unfolded site frequency spectrum left by hitchhiking in the genomic region of a sweep in a population occupying a 1D range. For such populations, sweeps...

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Identifiers

PMID: 36094352
DOI: 10.1093/genetics/iyac139
PMCID: PMC9630975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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