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Article

The hitchhiking effect on the site frequency spectrum of DNA polymorphisms.

Genetics - 1 Jun 1995

Braverman J M, Hudson R R, Kaplan N L, Langley C H, Stephan W

Abstract excerpt

The level of DNA sequence variation is reduced in regions of the Drosophila melanogaster genome where the rate of crossing over per physical distance is also reduced. This observation has been interpreted as support for the simple model of genetic hitchhiking, in which directional selection on rare variants, e.g., newly arising advantageous mutants, sweeps linked neutral alleles to fixation, thus eliminating...

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Identifiers

PMID: 7498754
DOI: 10.1093/genetics/140.2.783
PMCID: PMC1206652

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The hitchhiking effect on the site frequency spectrum of DNA polymorphisms.PMID 7498754Read ↗

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