The hitchhiking effect on the site frequency spectrum of DNA polymorphisms.

doi:10.1093/genetics/140.2.783

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Article

The hitchhiking effect on the site frequency spectrum of DNA polymorphisms.

Genetics - 1 Jun 1995

Braverman J M, Hudson R R, Kaplan N L, Langley C H, Stephan W

Abstract excerpt

The level of DNA sequence variation is reduced in regions of the Drosophila melanogaster genome where the rate of crossing over per physical distance is also reduced. This observation has been interpreted as support for the simple model of genetic hitchhiking, in which directional selection on ra...

Topics

Animals
DNA
Drosophila melanogaster
Genetic Variation
Models, Genetic
Polymorphism, Genetic

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