Article
Persistence of Rare Salmonella Typhi Genotypes Susceptible to First-Line Antibiotics in the Remote Islands of Samoa.
mBio - 26 Oct 2022
Sikorski Michael J, Hazen Tracy H, Desai Sachin N, Nimarota-Brown Susana, Tupua Siaosi, Sialeipata Michelle, Rambocus Savitra, Ingle Danielle J, Duchene Sebastian, Ballard Susan A, Valcanis Mary, Zufan Sara, Ma Jianguo, Sahl Jason W, Maes Mailis, Dougan Gordon, Thomsen Robert E, Robins-Browne Roy M, Howden Benjamin P, Naseri Take K, Levine Myron M, Rasko David A
Abstract excerpt
For decades, the remote island nation of Samoa (population ~200,000) has faced endemic typhoid fever despite improvements in water quality, sanitation, and economic development. We recently described the epidemiology of typhoid fever in Samoa from 2008 to 2019 by person, place, and time; however, the local Salmonella enterica serovar Typhi (S. Typhi) population structure, evolutionary origins, and genomic...
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