Effects of GRIN2B , GRIA1 , and BDNF Polymorphisms on the Therapeutic Action of Ketamine and Esketamine in Treatment-Resistant Depression Patients: Secondary Analysis From a Randomized Clinical Trial.

doi:10.1097/WNF.0000000000000517

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Article

Effects of GRIN2B , GRIA1 , and BDNF Polymorphisms on the Therapeutic Action of Ketamine and Esketamine in Treatment-Resistant Depression Patients: Secondary Analysis From a Randomized Clinical Trial.

Clinical neuropharmacology - 1 Jan 2022

Beanes Graziele, Caliman-Fontes Ana Teresa, Souza-Marques Breno, Silva Hátilla Dos Santos, Leal Gustavo C, Carneiro Beatriz Alves, Guerreiro-Costa Lívia N F, Figueiredo Alexandre V, Figueiredo Camila Alexandrina V, Lacerda Acioly L T, Costa Ryan Dos S, Quarantini Lucas C

Abstract excerpt

OBJECTIVE: This study aimed to evaluate the effect of genetic variants in glutamate ionotropic receptor N-methyl- d -aspartate type subunit 2B ( GRIN2B ), glutamate ionotropic receptor α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid type subunit 1 ( GRIA1 ), and brain-derived neurotrophic factor ( BDNF ) genes on therapeutic response, remission, and total Montgomery-Åsberg Depression Rating Scale scores...

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Identifiers

PMID: 36093918
DOI: 10.1097/WNF.0000000000000517

Genes

BDNF
GRIA1
GRIN2B
TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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