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Development of a rapid and accurate CRISPR/Cas13-based diagnostic test for GII.4 norovirus infection

24 Aug 2022

Abstract excerpt

Genogroup II genotype 4 (GII.4) norovirus causes acute gastroenteritis in children, and its infection is more severe than that of other genotypes. Early and precise detection and treatment are critical for controlling its spread and reducing the severity of infection. In this study, a rapid and efficient isothermal assay for the GII.4 norovirus detection (GII.4-CRISPR detection) was developed based on the...

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PMID: 36090107
DOI: 10.3389/fmicb.2022.912315

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