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Article

Phenotypes based Classification of Blood-Brain-Barrier Drugs using Feature Selection Methods and Extreme Gradient Boosting.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jul 2022

Ramakrishnan Manuskendan Subha, Ganapathy Nagarajan

Abstract excerpt

In this work, an attempt has been made to discriminate drug with blood brain barrier (BBB) permeability using clinical phenotypes and extreme gradient boosting (XGBoost) methods. For this, the drug name and their clinical phenotypes namely side effects and indications are obtained from public available database. Prominent clinical phenotypes are selected using genetic algorithm (GA) and binary particle swarm...

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Identifiers

PMID: 36085687
DOI: 10.1109/EMBC48229.2022.9871431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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