Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

m6A-YTHDF1-mediated TRIM29 upregulation facilitates the stem cell-like phenotype of cisplatin-resistant ovarian cancer cells.

Biochimica et biophysica acta. Molecular cell research - 1 Jan 2021

Hao Liang, Wang Jia-Mei, Liu Bao-Qin, Yan Jing, Li Chao, Jiang Jing-Yi, Zhao Fu-Ying, Qiao Huai-Yu, Wang Hua-Qin

Abstract excerpt

Ovarian cancer is the deadliest gynaecologic malignancy, and the five-year survival rate of patients is less than 35% worldwide. Cancer stem cells (CSCs) are a population of cells with stem-like characteristics that are thought to cause chemoresistance and recurrence. TRIM29 is aberrantly expressed in various cancers and associated with cancer development and progression. Previous studies showed that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Cisplatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Drug Resistance, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to Neoplastic Stem Cells

Share to Ovarian Neoplasms

Share to RNA-Binding Proteins

Source

Identifiers

PMID: 33011193
DOI: 10.1016/j.bbamcr.2020.118878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

m6A-YTHDF1-mediated TRIM29 upregulation facilitates the stem cell-like phenotype of cisplatin-resistant ovarian cancer cells.PMID 33011193Read ↗

TRIM28 in cancer and cancer therapySemantic proximity Read ↗

E3 Ubiquitin Ligase TRIM29 Promotes Pancreatic Cancer Growth and Progression via Stabilizing Yes-associated Protein 1Semantic proximity Read ↗

High expression of TRIM24 predicts worse prognosis and promotes proliferation and metastasis of epithelial ovarian cancerSemantic proximity Read ↗

Circ_RNF13 Regulates the Stemness and Chemosensitivity of Colorectal Cancer by Transcriptional Regulation of DDX27 Mediated by TRIM24 StabilizationSemantic proximity Read ↗

TRIM29 prevents hepatocellular carcinoma progression by inhibiting Wnt/β-catenin signaling pathwaySemantic proximity Read ↗

The complexity of TRIM28 contribution to cancerSemantic proximity Read ↗

CSN6–TRIM21 axis instigates cancer stemness during tumorigenesisSemantic proximity Read ↗

Identification of a Novel Oncogenic Fusion Gene SPON1-TRIM29 in Clinical Ovarian Cancer That Promotes Cell and Tumor Growth and Enhances Chemoresistance in A2780 CellsSemantic proximity Read ↗

Investigation of novel regulatory mechanisms of TRIM29 in BC, GC, and CRC patients: systems biology approach to find novel non-coding interactionsSemantic proximity Read ↗

High expression of TRIM29 (ATDC) contributes to poor prognosis and tumor metastasis by inducing epithelial-mesenchymal transition in osteosarcomaSemantic proximity Read ↗

TRIM58 downregulation maintains stemness via MYH9-GRK3-Hippo/YAP axis activation in triple-negative breast cancer stem cellsSemantic proximity Read ↗

Modeling platinum resistance in a stem-like patient-derived ovarian cancer sampleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.