Article
Polygenic determinants of severe hypertriglyceridemia.
Human molecular genetics - 15 Sept 2008
Wang Jian, Ban Matthew R, Zou Guang Yong, Cao Henian, Lin Tim, Kennedy Brooke A, Anand Sonia, Yusuf Salim, Huff Murray W, Pollex Rebecca L, Hegele Robert A
Abstract excerpt
Recent genome-wide association (GWA) studies have identified new genetic determinants of complex quantitative traits, including plasma triglyceride (TG). We hypothesized that common variants associated with mild TG variation identified in GWA studies would also be associated with severe hypertriglyceridemia (HTG). We studied 132 patients of European ancestry with severe HTG (fasting plasma TG > 10 mmol/l), who...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.