Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer genome and tumor microenvironment: Reciprocal crosstalk shapes lung cancer plasticity

12 Aug 2022

Abstract excerpt

Lung cancer classification and treatment has been revolutionized by improving our understanding of driver mutations and the introduction of tumor microenvironment (TME)-associated immune checkpoint inhibitors. Despite the significant improvement of lung cancer patient survival in response to either oncogene-targeted therapy or anticancer immunotherapy, many patients show initial or acquired resistance to these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer Immunotherapy and Biomarkers
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36074553
DOI: 10.7554/elife.79895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer genome and tumor microenvironment: Reciprocal crosstalk shapes lung cancer plasticityPMID 36074553Read ↗

Tumor microenvironment and drug resistance in lung adenocarcinoma: molecular mechanisms, prognostic implications, and therapeutic strategiesSemantic proximity Read ↗

Molecular Landscape and Therapeutic Strategies of Lung Cancer Lineage PlasticitySemantic proximity Read ↗

New evaluation of the tumor immune microenvironment of non-small cell lung cancer and its association with prognosisSemantic proximity Read ↗

Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment.Semantic proximity Read ↗

Genetic drivers of tumor microenvironment and immunotherapy resistance in non-small cell lung cancer: the role of KEAP1 , SMARCA4 , and PTEN mutationsSemantic proximity Read ↗

Microenvironment Analysis of Prognosis and Molecular Signature of Immune-Related Genes in Lung Adenocarcinoma.Semantic proximity Read ↗

Identification and validation of tumor environment phenotypes in lung adenocarcinoma by integrative genome-scale analysis.Semantic proximity Read ↗

The Importance of the Immune System and Molecular Cell Signaling Pathways in the Pathogenesis and Progression of Lung CancerSemantic proximity Read ↗

Persistent lineage plasticity driving lung cancer development and progressionSemantic proximity Read ↗

An Investigation of the Immune Microenvironment and Genome during Lung Adenocarcinoma DevelopmentSemantic proximity Read ↗

The tumor environment immune phenotype of LUSC by genome-wide analysis.Semantic proximity Read ↗

Phenotype molding of stromal cells in the lung tumor microenvironment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.