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Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer

5 Sept 2022

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer-related deaths worldwide. Aberrant cellular metabolism is a hallmark of cancer cells, and disturbed metabolism showed clinical significance in CRC. The membrane-associated RING-CH 8 (MARCH8) protein, the first MARCH E3 ligase, plays an oncogenic role and serves as a prognostic marker in multiple cancers, however, the...

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PMID: 36064706
DOI: 10.1186/s12967-022-03608-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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