Article
Transcriptome-module phenotype association study implicates extracellular vesicles biogenesis in Plasmodium falciparum artemisinin resistance.
Frontiers in cellular and infection microbiology - 1 Jan 2022
Tandoh Kwesi Z, Hagan Oheneba C, Wilson Michael D, Quashie Neils B, Duah-Quashie Nancy O
Abstract excerpt
Plasmodium falciparum malaria is still an important disease in sub-Saharan Africa (sSA). Great strides have been made in its control spear-headed by artemisinin (ART)-based combination therapies (ACTs). However, concerns about the imminent spread of ART-resistant (ARTr) malaria parasites to sSA threaten gains already made. Attempts to mitigate this risk have highlighted the need to discover novel P. falciparum...
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