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Pro-tumorigenic role of type 2 diabetes-induced cellular senescence in colorectal cancer

18 Aug 2022

Abstract excerpt

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. The disease still remains incurable and highly lethal in the advanced stage, representing a global health concern. Therefore, it is essential to understand the causes and risk factors leading to its development. Because age-related cellular senescence and type 2 diabetes (T2D) have been recognised as risk factors for CRC...

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PMID: 36059680
DOI: 10.3389/fonc.2022.975644

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