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C allele in transforming growth factor-β1 rs1800471 gene polymorphisms might indicate a protective feature in encapsulating peritoneal sclerosis development.

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy - 1 Apr 2023

Bora Feyza, Aslan Bengisu, Sarı Funda, Yılmaz Fatih, Ersoy Fettah Fevzi, Köksoy Sadi, Özdem Sebahat, Küçükçetin İkbal Özen, Sipahioğlu Murat, Karakaya İbrahim, Koç Yener, Ulu Memnune Sena

Abstract excerpt

INTRODUCTION: Peritoneal fibrosis may progress in peritoneal dialysis (PD) patients to a fatal clinical condition called encapsulating peritoneal sclerosis (EPS). Transforming growth factor (TGF)-β plays a pivotal role in the pathogenesis of peritoneal fibrosis. We aimed to investigate the association among polymorphisms in the gene encoding TGF-β1, which were -509C/T (rs1800469), +869T/C (rs1982073), and +915G/C...

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PMID: 36054236
DOI: 10.1111/1744-9987.13913

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