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Detection of diphtheria toxin production by toxigenic corynebacteria using an optimized Elek test

2 Sept 2022

Abstract excerpt

PURPOSE: Diphtheria, still present in many countries of the world, is caused by toxigenic strains of species of the Corynebacterium diphtheriae complex, mainly Corynebacterium diphtheriae and the emerging zoonotic pathogen C. ulcerans. The immunoprecipitation test according to Elek is the gold standard for detection of the major virulence factor diphtheria toxin (DT) in toxigenic corynebacteria. Due to its...

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PMID: 36053480
DOI: 10.1007/s15010-022-01903-x

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