Aldehyde dehydrogenase 2 rs671 polymorphism and multiple diseases: protocol for a quantitative umbrella review of meta-analyses.

doi:10.1186/s13643-022-02050-y

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Aldehyde dehydrogenase 2 rs671 polymorphism and multiple diseases: protocol for a quantitative umbrella review of meta-analyses.

Systematic reviews - 2 Sept 2022

He Zhengting, Guo Qi, Ling Yikai, Hong Chuan, Liu Yuqing, Jin Xurui, Thanaporn Porama, Zhao Duan, Wang Leiting, Liu Liang, Yan Lijing L

Abstract excerpt

BACKGROUND: The mutant allele (*2) of aldehyde dehydrogenase type 2 (ALDH2) caused by a single nucleotide variant (rs671) inhibits enzymatic activity and is associated with multiple diseases. In recent years, an explosive number of original studies and meta-analyses have been conducted to examine the associations of ALDH2 rs671 polymorphism with diseases. Due to conflicting results, the overall associations of...

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Alcohol Consumption and Health Effects
Alcoholism and Thiamine Deficiency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Aldehyde Dehydrogenase, Mitochondrial

Alleles

Meta-Analysis as Topic

Neurodegenerative Diseases

Polymorphism, Single Nucleotide

Systematic Reviews as Topic

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Identifiers

PMID: 36050775
DOI: 10.1186/s13643-022-02050-y
PMCID: PMC9438126

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