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Article

Development and Characterization of Synthetic Norovirus RNA for Use in Molecular Detection Methods.

Annals of laboratory medicine - 1 Jan 2023

Cho Eun-Jung, Cha Younggil, Lee Su Kyung, Kim Han-Sung, Kim Jae-Seok, Lee Eun Jin, Lee Nuri, Hong Ki Ho, Huh Hee Jin, Cha Young Joo, Kim Hyun Soo

Abstract excerpt

Background: Reference materials are essential for the quality assurance of molecular detection methods. We developed and characterized synthetic norovirus GI and GII RNA reference materials. Methods: Norovirus GI and GII RNA sequences including the ORF1-ORF2 junction region were designed based on 1,495 reported norovirus sequences and synthesized via plasmid preparation and in vitro transcription. The synthetic...

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Identifiers

PMID: 36045055
DOI: 10.3343/alm.2023.43.1.38
PMCID: PMC9467847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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