Article
The g.-165 T>C Rather than Methylation Is Associated with Semen Motility in Chinese Holstein Bulls by Regulating the Transcriptional Activity of the HIBADH Gene.
PloS one - 1 Jan 2015
Zhang Shuai, Zhang Yan, Yang Chunhong, Ju Zhihua, Wang Xiuge, Jiang Qiang, Sun Yan, Huang Jinming, Zhong Jifeng, Wang Changfa
Abstract excerpt
The 3-hydroxyisobutyrate dehydrogenase (HIBADH) is regarded as a human sperm-motility marker. However, the molecular mechanisms involved in the regulation of expression of the HIBADH gene in bulls remain largely unknown. HIBADH was detected in the testis, epididymis, and sperm via reverse transcription polymerase chain reaction and Western blot analysis. It is also expressed in the seminiferous epithelium,...
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