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Article

The role of RNA uptake in platelet heterogeneity

1 Jan 2017

Abstract excerpt

The role of platelets in regulating vascular homeostasis has expanded beyond mediation of haemostasis and thrombosis. The discovery of platelet RNA and the presence of subpopulations of platelets containing varying amounts of RNA suggest a role for platelet transcripts in vascular function. As the RNA in anucleated platelets is biologically functional and may transfer to other vascular cells, we hypothesised that...

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PMID: 28276570
DOI: 10.1160/th16-11-0873

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