Article
Modular microsystem for the isolation, enumeration, and phenotyping of circulating tumor cells in patients with pancreatic cancer.
Analytical chemistry - 1 Oct 2013
Kamande J W, Hupert M L, Witek M A, Wang H, Torphy R J, Dharmasiri U, Njoroge S K, Jackson J M, Aufforth R D, Snavely A, Yeh J J, Soper S A
Abstract excerpt
In this manuscript, we discuss the development and clinical use of a thermoplastic modular microsystem for the high-throughput analysis of CTCs directly from whole blood. The modular system offers some innovative features that address challenges currently associated with many CTC platforms; it can exhaustively process 7.5 mL of blood in less than 45 min with recoveries >90%. In addition, the system automates the...
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