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Article

Potential Mediators of Causal Associations of Circulating Triglycerides With Blood Pressure: Evidence From Genetic and Observational Data.

Hypertension (Dallas, Tex. : 1979) - 1 Nov 2022

Liu Lian Yong, Gu Qing, Hu Xue, Fan Jie, Liu Xing Zhen

Abstract excerpt

BACKGROUND: Existing evidence indicates that elevated triglycerides may affect blood pressure, but the underlying mechanisms are not fully understood. Herein, we aim to identify the intermediaries of associations of triglyceride with systolic blood pressure and diastolic blood pressure using the Mendelian randomization (MR) framework. METHODS: Triglyceride-associated single nucleotide polymorphisms were extracted...

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PMID: 36004668
DOI: 10.1161/HYPERTENSIONAHA.122.19510

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