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Article

Novel insights into the causal effects of triglycerides to high density lipoprotein cholesterol ratio on blood pressure.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Apr 2026

Wan Aihong, Han Yuqin, Wu Lingling, Wei Yuanhao, Xiang Xiqiao, Chen Yi, Chen Jinquan, Song Aihua, Zhao Kun

Abstract excerpt

BACKGROUND AND AIMS: Previous studies have suggested links between the triglycerides to high-density lipoprotein cholesterol (TG:HDL-C) ratio on blood pressure (BP) traits and hypertension (HTN) risk. However, the causal relationships remain unclear. METHODS AND RESULTS: We conducted genome-wide linkage disequilibrium score regression (LDSC), two-sample Mendelian randomization (MR), colocalization, reverse, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41484026
DOI: 10.1016/j.numecd.2025.104474

Genes

TG
DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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