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Characterization of stem-cell-derived islets during differentiation and after implantation

1 Aug 2022

Abstract excerpt

Recapitulation of embryonic pancreatic development has enabled development of methods for in vitro islet cell differentiation using human pluripotent stem cells (hPSCs), which have the potential to cure diabetes. Advanced methods for optimal generation of stem-cell-derived islets (SC-islets) has enabled successful diabetes reversal in rodents and shown promising early clinical trial outcomes. The main impediment...

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Diabetes and associated disorders
Diabetes Management and Research
Pancreatic function and diabetes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36001981
DOI: 10.1016/j.celrep.2022.111238

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