Liver Cirrhosis Patients Homozygous for MTHFR C677T Develop Portal Vein Thrombosis 8 Years Earlier Than Wild Type.

doi:10.1007/s10620-022-07666-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Liver Cirrhosis Patients Homozygous for MTHFR C677T Develop Portal Vein Thrombosis 8 Years Earlier Than Wild Type.

Digestive diseases and sciences - 1 Apr 2023

Ames Paul R J, D'Andrea Giovanna, Arcaro Alessia, Marottoli Vincenzo, Iannaccone Luigi, Maraglione Maurizio, Gentile Fabrizio

Abstract excerpt

BACKGROUND AND AIM: Age at portal vein thrombosis (PVT) in liver cirrhosis (LC) carriers of the methylene tetrahydrofolate reductase (MTHFR) rs1801133 (C → T667 transition) polymorphism has never been addressed; we compared age at PVT in LC patients genotyped for the MTHFR and explored the interrelated clinical and laboratory factors predicting age at PVT. APPROACH AND RESULTS: Retrospective cross-sectional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Homocysteine

Share to Liver Cirrhosis

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Portal Vein

Share to Protein C

Share to Venous Thrombosis

Source

Open in PubMed

Identifiers

PMID: 35999432
DOI: 10.1007/s10620-022-07666-7

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Liver Cirrhosis Patients Homozygous for MTHFR C677T Develop Portal Vein Thrombosis 8 Years Earlier Than Wild Type.PMID 35999432Read ↗

Homozygous MTHFR C677T carriers develop idiopathic portal vein thrombosis 20 years earlier than wild type.Semantic proximity Read ↗

Homozygous Mthfr C677t Carriers Develop Idiopathic Portal Vein Thrombosis Twenty Years Earlier Than Wild TypeSemantic proximity Read ↗

Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.Semantic proximity Read ↗

Inherited coagulation disorders in cirrhotic patients with portal vein thrombosis.Semantic proximity Read ↗

Portal vein thrombosis in patients with liver cirrhosis: Risk factors and clinical presentationSemantic proximity Read ↗

Novel insights into the development of portal vein thrombosis in cirrhosis patients.Semantic proximity Read ↗

Thrombophilic genetic factors PAI-1 4G-4G and MTHFR 677TT as risk factors of alcohol, cryptogenic liver cirrhosis and portal vein thrombosis, in a Caucasian population.Semantic proximity Read ↗

Janus Kinase-2 Mutation Associated Portal Vein Thrombosis Complicating Liver Cirrhosis and Hepatocellular Carcinoma.Semantic proximity Read ↗

Earlier onset of peripheral arterial thrombosis in homozygous MTHFR C677T carriers than in other MTHFR genotypes: a cohort study.Semantic proximity Read ↗

Homozygous MTHFR C667T carriers ≤45 years old develop central retinal vein occlusion five years earlier than wild type.Semantic proximity Read ↗

Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors.Semantic proximity Read ↗

Portal vein thrombosis: what is the role of genetics?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.