Article
Homozygous MTHFR C677T carriers develop idiopathic portal vein thrombosis 20 years earlier than wild type.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2024
Ames Paul Rj, D'Andrea Giovanna, Arcaro Alessia, Marottoli Vincenzo, Iannaccone Luigi, Margaglione Maurizio, Gentile Fabrizio
Abstract excerpt
The aim of this study was to evaluate the impact of methylene tetrahydrofolate reductase (MTHFR) rs1801133 (C→T667 transition) on age at first idiopathic portal vein thrombosis (PVT) and to identify clinical and/or laboratory variables influencing age at first PVT, including plasma homocysteine and the prothrombin rs1799963 PT (G→A transition at position 20210) (PT) mutation. A retrospective cross-sectional...
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