Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Earlier onset of peripheral arterial thrombosis in homozygous MTHFR C677T carriers than in other MTHFR genotypes: a cohort study.

Clinical and experimental medicine - 1 Jun 2023

Ames Paul R J, D'Andrea Giovanna, Marottoli Vincenzo, Arcaro Alessia, Iannaccone Luigi, Maraglione Maurizio, Gentile Fabrizio

Abstract excerpt

To investigate whether age at first presentation of pure peripheral arterial thrombosis (PAT) in lower and upper limbs and in the splanchnic circulation occurs earlier in carriers of the methylenetetrahydrofolate reductase (MTHFR) T677T genotype compared to the heterozygous and wild type and to identify predictors of a possible earlier onset. Retrospective cohort study on 27 MTHFR TT, 29 MTHFR TC and 29 MTHFR CC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Thrombosis

Source

Identifiers

PMID: 35362772
DOI: 10.1007/s10238-022-00819-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Earlier onset of peripheral arterial thrombosis in homozygous MTHFR C677T carriers than in other MTHFR genotypes: a cohort study.PMID 35362772Read ↗

Homozygous MTHFR C677T carriers develop idiopathic portal vein thrombosis 20 years earlier than wild type.Semantic proximity Read ↗

Homozygous Mthfr C677t Carriers Develop Idiopathic Portal Vein Thrombosis Twenty Years Earlier Than Wild TypeSemantic proximity Read ↗

Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients.Semantic proximity Read ↗

Clinical significance of determining plasma homocysteine: case-control study on arterial and venous thrombotic patients.Semantic proximity Read ↗

Juvenile patients with the homozygous MTHFR C677T genotype develop ischemic stroke 5 years earlier than wild type.Semantic proximity Read ↗

The mutation Ala677-->Val in the methylene tetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis.Semantic proximity Read ↗

Polymorphisms C677T and A1298C of MTHFR Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease.Semantic proximity Read ↗

Association of methylenetetrahydrofolate reductase (MTHFR-677 and MTHFR-1298) genetic polymorphisms with occlusive artery disease and deep venous thrombosis in Macedonians.Semantic proximity Read ↗

MTHFR 677C>T (rs1801133) variant is associated with homocysteinemia but not with clinical severity in patients with peripheral arterial occlusive diseaseSemantic proximity Read ↗

Potential Risk Factors Associated With Vascular Diseases in Patients Receiving Treatment for Hypertension.Semantic proximity Read ↗

C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients.Semantic proximity Read ↗

[Molecular genetic markers of predisposition to thrombosis in adolescents with essential hypertension ].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.