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Article

Chronotype and insomnia may affect the testosterone levels with a sexual difference: a Mendelian randomization.

Journal of endocrinological investigation - 1 Jan 2023

Yuan C, Jian Z, Jin X

Abstract excerpt

OBJECTIVE: To evaluate the causal effects of sleep traits (i.e., chronotype, insomnia, and sleep duration) on bioavailable testosterone (BT), sex hormone-binding globulin (SHBG), and total testosterone (TT) levels in women and men. METHODS: We performed Mendelian randomization (MR) using random-effect inverse-variance weighted (IVW) and 7 other MR analyses. Exposure data for sleep traits were obtained from the...

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Identifiers

PMID: 35997959
DOI: 10.1007/s40618-022-01890-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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