Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Obesity-related glomerulopathy in the presence of APOL1 risk alleles.

BMJ case reports - 19 Aug 2022

Valdez Imbert Ronald, Hti Lar Seng Nang San, Stokes Michael B, Jim Belinda

Abstract excerpt

Nephropathic apolipoprotein L1 (APOL1) risk alleles (G1/G2) have been associated with focal segmental glomerulosclerosis, HIV-associated nephropathy, Systemic lupus erythematosus (SLE)-associated collapsing glomerulopathy and other glomerulonephritides. These alleles confer protection from Trypanosoma brucei infections which are enriched in sub-Saharan African populations. We present a young woman with obesity,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Apolipoprotein L1
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Glomerulosclerosis, Focal Segmental

Share to Obesity

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 35985743
DOI: 10.1136/bcr-2022-249624
PMCID: PMC9396144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Obesity-related glomerulopathy in the presence of APOL1 risk alleles.PMID 35985743Read ↗

APOL1 null alleles from a rural village in India do not correlate with glomerulosclerosis.Semantic proximity Read ↗

Apolipoprotein L1 (APOL1) and Nephropathy.Semantic proximity Read ↗

Population genetics of chronic kidney disease: the evolving story of APOL1.Semantic proximity Read ↗

APOL1 nephropathy: from gene to mechanisms of kidney injury.Semantic proximity Read ↗

Gene of the month: APOL1.Semantic proximity Read ↗

G1 is the major APOL1 risk allele for hypertension-attributed nephropathy in Central AfricaSemantic proximity Read ↗

APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy.Semantic proximity Read ↗

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis.Semantic proximity Read ↗

Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.Semantic proximity Read ↗

Association of trypanolytic ApoL1 variants with kidney disease in African Americans.Semantic proximity Read ↗

Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.Semantic proximity Read ↗

Carrying APOL1 G1 allele is associated with cardiovascular complications during COVID-19 in an admixed population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.