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Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells

16 Aug 2022

Abstract excerpt

BACKGROUND: 3D collagen scaffold culture is a good tool to study glioma metastasis and recurrence in vitro. METHODS: The effect of 3D collagen culture on the colony formation, the sphere formation, and drug sensitivity of glioma cells was observed by soft-agar colony formation assays, sphere formation assays, and CCK-8 assays, respectively. 3D-glioma-drug genes were identified by previous results and online...

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PMID: 35981653
DOI: 10.1016/j.bbadis.2022.166522

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