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Article

Novel mutations in antiviral multiresistant HSV-2 genital lesion: A case report.

Journal of medical virology - 1 Dec 2022

Khellaf Lucas, Bouscarat Fabrice, Burrel Sonia, Fidouh Nadhira, Hachon Lorry, Bucau Margot, Lariven Sylvie, Boutolleau David, Joly Véronique, Ghosn Jade, Le Pluart Diane, Thy Michaël

Abstract excerpt

HSV-2 antiviral resistance mainly occurs in immunocompromised patients and especially in HIV-positive individuals receiving long-term antiviral treatment. Those situations can be challenging as few alternatives are available for HSV infection management. To describe clinical and virological significance of two novel potential HSV-2 resistance mutations after treating an obese patient with a pseudotumoral genital...

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PMID: 35973907
DOI: 10.1002/jmv.28070

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