Article
Prognostic value of baseline genetic features and newly identified TP53 mutations in advanced breast cancer.
Molecular oncology - 1 Oct 2022
Zhang Lanxin, Sun Siwen, Zhao Xiaotian, Liu Jingwen, Xu Yang, Xu Lingzhi, Song Chen, Li Na, Yu Jing, Zhao Shanshan, Yu Peiyao, Fang Fengqi, Xie Jiping, Ji Xuening, Yu Ruoying, Ou Qiuxiang, Zhao Zuowei, Li Man
Abstract excerpt
Approximately 30% of breast cancer (BC) patients suffer from disease relapse after definitive treatment. Monitoring BC at baseline and disease progression using comprehensive genomic profiling would facilitate the prediction of prognosis. We retrospectively studied 101 BC patients ultimately experiencing relapse and/or metastases. The baseline and circulating tumor DNA-monitoring cohorts included patients with...
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