Article
Identification of mutation patterns and circulating tumour DNA-derived prognostic markers in advanced breast cancer patients.
Journal of translational medicine - 13 May 2022
Liao Hao, Zhang Jiayang, Zheng Tiantian, Liu Xiaoran, Zhong Jianxin, Shao Bin, Dong Xiaoxi, Wang Xiaohong, Du Pan, King Bonnie L, Jia Shidong, Yu Jianjun, Li Huiping
Abstract excerpt
BACKGROUND: The correlations between circulating tumour DNA (ctDNA)-derived genomic markers and treatment response and survival outcome in Chinese patients with advanced breast cancer (ABC) have not been extensively characterized. METHODS: Blood samples from 141 ABC patients who underwent first-line standard treatment in Peking University Cancer Hospital were collected. A next-generation sequencing based liquid...
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