Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex

22 Jul 2022

Abstract excerpt

Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Drug Discovery Methods
Share to Lipid Membrane Structure and Behavior
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35936792
DOI: 10.3389/fmolb.2022.846996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 ComplexPMID 35936792Read ↗

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 ComplexSemantic proximity Read ↗

Insilico study on the effect of SARS-CoV-2 RBD hotspot mutants' interaction with ACE2 to understand the binding affinity and stability.Semantic proximity Read ↗

Key residues of the receptor binding domain in the spike protein of SARS-CoV-2 mediating the interactions with ACE2: a molecular dynamics studySemantic proximity Read ↗

Structural and computational insights into the SARS-CoV-2 Omicron RBD-ACE2 interactionSemantic proximity Read ↗

Structural and computational insights into the SARS-CoV-2 Omicron RBD-ACE2 interactionSemantic proximity Read ↗

Molecular dynamics study on the strengthening behavior of Delta and Omicron SARS-CoV-2 spike RBD improved receptor-binding affinitySemantic proximity Read ↗

Differential Interactions between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of ConcernSemantic proximity Read ↗

Binding Interactions between RBD of Spike-Protein and Human ACE2 in Omicron variantSemantic proximity Read ↗

Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike – ACE2 complexes reveal distinct changes between both variantsSemantic proximity Read ↗

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibilitySemantic proximity Read ↗

Molecular Dynamics Simulations Studies On The Effects Of Mutations On The Binding Affinities Between SARS-CoV-2 Spike RBD And Human ACE2Semantic proximity Read ↗

Studying the Effects of ACE2 Mutations on the Stability, Dynamics, and Dissociation Process of SARS-CoV‑2 S1/hACE2 ComplexesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.