Article
Association of CDK6 gene polymorphisms with Behcet's disease in a Han Chinese population.
Experimental eye research - 1 Oct 2022
Cai Shiya, Zhang Jun, Zhou Chunya, Shi Wenjian, Gao Yingying, Chang Rui, Tan Handan, Wang Qingfeng, Ye Xingsheng, Cao Qingfeng, Zhou Qingyun, Yang Peizeng, Hu Jianmin
Abstract excerpt
Cyclin-dependent kinases 4/6 (CDK4/6) and D1-type cyclins (CCND1) can regulate the pro-inflammatory functions of various cytokines during the inflammatory response. This study investigated the association between CDK4/6-CCND1 variants and susceptibility in patients with Behcet's disease (BD). This case-control study enrolled 542 patients with BD and 754 healthy controls. Fourteen tagged single nucleotide...
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