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Article

The second polar body contributes to the fate asymmetry in the mouse embryo

7 Jan 2022

Abstract excerpt

The polar bodies (PBs) are extruded microcells during oocyte meiosis and generally regarded as inessentials for embryonic development. Therefore, PBs have been widely used as important materials for pre-implantation genetic diagnosis in human. Here we report that the second PB (PB2) in the mouse zygote may play roles in cell-fate specification and post-implantation development. A subset of mRNAs encoding...

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PMID: 35919785
DOI: 10.1093/nsr/nwac003

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