Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SUMO Modification of Histone Demethylase KDM4A in Kaposi’s Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma

1 Aug 2022

Abstract excerpt

PEL is an aggressive and untreatable B-cell lymphoma caused by KSHV infection. Therefore, new therapeutic approaches for PEL need to be investigated. Since simultaneous induction of KSHV reactivation and apoptosis can directly kill PEL cells, they have been applied in the treatment of this hematologic malignancy and have made progress. Epigenetic therapy with histone deacetylase (HDAC) inhibitors has been proved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lymphoma Diagnosis and Treatment
Share to T-cell and Retrovirus Studies
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35914074
DOI: 10.1128/jvi.00755-22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SUMO Modification of Histone Demethylase KDM4A in Kaposi’s Sarcoma-Associated Herpesvirus-Induced Primary Effusion LymphomaPMID 35914074Read ↗

Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomasSemantic proximity Read ↗

Rewriting Viral Fate: Epigenetic and Transcriptional Dynamics in KSHV InfectionSemantic proximity Read ↗

Expression of MUM1/IRF4 selectively clusters with primary effusion lymphoma among lymphomatous effusions: implications for disease histogenesis and pathogenesisSemantic proximity Read ↗

Oncovirus Kaposi Sarcoma Herpesvirus (KSHV) Represses Tumor Suppressor PDLIM2 to Persistently Activate Nuclear Factor κB (NF-κB) and STAT3 Transcription Factors for Tumorigenesis and Tumor MaintenanceSemantic proximity Read ↗

Distinct Subsets of Primary Effusion Lymphoma Can Be Identified Based on Their Cellular Gene Expression Profile and Viral AssociationSemantic proximity Read ↗

Modulation of Cellular CpG DNA Methylation by Kaposi's Sarcoma-Associated HerpesvirusSemantic proximity Read ↗

Analysis of the ubiquitin-modified proteome identifies novel host factors in Kaposi’s sarcoma herpesvirus lytic reactivationSemantic proximity Read ↗

Histone Deacetylase Classes I and II Regulate Kaposi's Sarcoma-Associated Herpesvirus ReactivationSemantic proximity Read ↗

Activation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) by Inhibitors of Class III Histone Deacetylases: Identification of Sirtuin 1 as a Regulator of the KSHV Life CycleSemantic proximity Read ↗

Nucleophosmin Phosphorylation by v-Cyclin-CDK6 Controls KSHV LatencySemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Contributes to Viral Latent Replication by Activating Phosphorylation of SurvivinSemantic proximity Read ↗

Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latencySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.