Article

Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomas

2026-01-28

Abstract excerpt

<h4>Summary/Abstract</h4> Histone methylation is a dynamic and reversible epigenetic modification that critically controls the progression of human diseases, including infections and cancers. Here we reported that histone lysine demethylases (KDMs) in the KDM5 family KDM5A/B play profound roles in suppressing lytic reactivation of oncogenic human herpesvirus 8 (HHV-8), i.e., Kaposi’s sarcoma-associated herpesviru...

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Literature Corpus work: 02e73daf-f613-57dd-a768-405a7231c1d7
DOI: 10.64898/2026.01.28.702275

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Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomasDOI 10.64898/2026.01.28.702275Read

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