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Article

Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron

29 Jul 2022

Abstract excerpt

SARS-CoV-2 variants with adaptive mutations have continued to emerge, causing fresh waves of infection even amongst vaccinated population. The development of broad-spectrum antivirals is thus urgently needed. We previously developed two hetero-bivalent nanobodies (Nbs), aRBD-2-5 and aRBD-2-7, with potent neutralization activity against the wild-type (WT) Wuhan isolated SARS-CoV-2, by fusing aRBD-2 with aRBD-5 and...

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Bacteriophages and microbial interactions
Monoclonal and Polyclonal Antibodies Research
SARS-CoV-2 and COVID-19 Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35906408
DOI: 10.1038/s41422-022-00700-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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