Article
miR-3156-5p is downregulated in serum of MEN1 patients and regulates expression of MORF4L2.
Endocrine-related cancer - 1 Oct 2022
Kooblall Kreepa G, Stokes Victoria J, Shariq Omair A, English Katherine A, Stevenson Mark, Broxholme John, Wright Benjamin, Lockstone Helen E, Buck David, Grozinsky-Glasberg Simona, Yates Christopher J, Thakker Rajesh V, Lines Kate E
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN1), caused by mutations in the MEN1 gene encoding menin, is an autosomal dominant disorder characterised by the combined occurrence of parathyroid, pituitary and pancreatic neuroendocrine tumours (NETs). Development of these tumours is associated with wide variations in their severity, order and ages (from <5 to >80 years), requiring life-long screening. To improve tumour...
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