Article
The P53 pathway: what questions remain to be explored?
Cell death and differentiation - 1 Jun 2006
Levine A J, Hu W, Feng Z
Abstract excerpt
The p53 pathway is composed of hundreds of genes and their products that respond to a wide variety of stress signals. These responses to stress include apoptosis, cellular senescence or cell cycle arrest. In addition the p53-regulated genes produce proteins that communicate these stress signals to adjacent cells, prevent and repair damaged DNA and create feedback loops that enhance or attenuate p53 activity and...
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