Article
HSPA8 Single-Nucleotide Polymorphism Is Associated with Serum HSC70 Concentration and Carotid Artery Atherosclerosis in Nonalcoholic Fatty Liver Disease.
Genes - 16 Jul 2022
Zhao Wenli, Mori Hitoe, Tomiga Yuki, Tanaka Kenichi, Perveen Rasheda, Mine Keiichiro, Inadomi Chika, Yoshioka Wataru, Kubotsu Yoshihito, Isoda Hiroshi, Kuwashiro Takuya, Oeda Satoshi, Akiyama Takumi, Zhao Ye, Ozaki Iwata, Nagafuchi Seiho, Kawaguchi Atsushi, Aishima Shinichi, Anzai Keizo, Takahashi Hirokazu
Abstract excerpt
There is an association between nonalcoholic fatty liver disease (NAFLD) and atherosclerosis, but the genetic risk of atherosclerosis in NAFLD remains unclear. Here, a single-nucleotide polymorphism (SNP) of the heat shock 70 kDa protein 8 (HSPA8) gene was analyzed in 123 NAFLD patients who had been diagnosed using a liver biopsy, and the NAFLD phenotype including the maximum intima-media thickness (Max-IMT) of...
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