Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The KIR2DL2/HLA-C1C1 Gene Pairing Is Associated With an Increased Risk of SARS-CoV-2 Infection.

Frontiers in immunology - 1 Jan 2022

Hu Song, Shao Zuoyu, Ni Wei, Sun Pan, Qiao Jialu, Wan Hexing, Huang Yi, Liu Xiaolong, Zhai Haoyang, Xiao Mingzhong, Sun Binlian

Abstract excerpt

SARS-CoV-2 is the causative agent for the global COVID-19 pandemic; however, the interaction between virus and host is not well characterized. Natural killer cells play a key role in the early phase of the antiviral response, and their primary functions are dependent on signaling through the killer cell immunoglobulin-like receptor (KIR). This study measured the association between KIR/HLA class I ligand pairings...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-C Antigens

Share to Pandemics

Share to Receptors, KIR2DL2

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 35874712
DOI: 10.3389/fimmu.2022.919110
PMCID: PMC9301464

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The KIR2DL2/HLA-C1C1 Gene Pairing Is Associated With an Increased Risk of SARS-CoV-2 Infection.PMID 35874712Read ↗

Analysis of KIR and HLA Polymorphism in Chinese Individuals With COVID-19.Semantic proximity Read ↗

Association of KIR gene polymorphisms with COVID-19 disease.Semantic proximity Read ↗

Killer-cell immunoglobulin-like receptor polymorphism is associated with COVID-19 outcome: Results of a pilot observational study.Semantic proximity Read ↗

Association study between killer immunoglobulin-like receptor polymorphisms and susceptibility to COVID-19 disease: a systematic review and meta-analysis.Semantic proximity Read ↗

HLA-DPB1*13:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID-19.Semantic proximity Read ↗

HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19.Semantic proximity Read ↗

Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection.Semantic proximity Read ↗

Association between HLA genotypes and COVID-19 susceptibility, severity and progression: a comprehensive review of the literature.Semantic proximity Read ↗

The natural killer cell-associated rs9916629-C allele is a novel genetic risk factor for fatal COVID-19.Semantic proximity Read ↗

Bioinformatic HLA Studies in the Context of SARS-CoV-2 Pandemic and Review on Association of HLA Alleles with Preexisting Medical Conditions.Semantic proximity Read ↗

The role of HLA genetic variants in COVID ‐19 susceptibility, severity, and mortality: A global reviewSemantic proximity Read ↗

Association between HLA gene polymorphisms and mortality of COVID-19: An in silico analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.