Article
Analysis of KIR and HLA Polymorphism in Chinese Individuals With COVID-19.
HLA - 1 Oct 2024
Tao Sudan, You Xuan, Norman Paul J, Kichula Katherine M, Dong Lina, Chen Nanying, He Ji, Zhang Wei, Zhu Faming
Abstract excerpt
Killer-cell immunoglobulin-like receptor (KIR) interactions with HLA class I have crucial roles in modulating NK cell function in response to viral infections. To explore the correlation between KIR/HLA and susceptibility to SARS-CoV-2 infection, we analysed polymorphism of KIR genes, haplotypes, HLA allotypes, and the interplay between KIR and HLA in individuals diagnosed with COVID-19. Compared to a population...
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