Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens

14 Jul 2022

Abstract excerpt

The baseline composition of T cells directly affects later response to pathogens, but the complexity of precursor states remains poorly defined. Here, we examined the baseline state of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific T cells in unexposed individuals. SARS-CoV-2–specific CD4 + T cells were identified in prepandemic blood samples by major histocompatibility complex (MHC) class...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to COVID-19 Impact on Reproduction
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35857619
DOI: 10.1126/sciimmunol.abn3127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigensPMID 35857619Read ↗

SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years.Semantic proximity Read ↗

Phenotypes and Functions of SARS-CoV-2-Reactive T CellsSemantic proximity Read ↗

SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cellsSemantic proximity Read ↗

COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2Semantic proximity Read ↗

The characterization of CD8 + T-cell responses in COVID-19Semantic proximity Read ↗

T Cell Immune Responses to SARS-CoV-2 Infection and VaccinationSemantic proximity Read ↗

Two sides of the same coin: Protective versus pathogenic CD4 + resident memory T cellsSemantic proximity Read ↗

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infectionSemantic proximity Read ↗

Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19Semantic proximity Read ↗

Virus-specific CD4(+) memory-phenotype T cells are abundant in unexposed adults.Semantic proximity Read ↗

Comprehensive longitudinal profiling of SARS-CoV-2-specific CD8 <sup>+</sup> T-cells reveal strong functional impairment and recognition bias as markers for disease severitySemantic proximity Read ↗

COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.