Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammation‐induced activation of the indoleamine 2,3‐dioxygenase pathway: Relevance to cancer‐related fatigue

27 Feb 2015

Abstract excerpt

Cancer-related fatigue (CRF) is a common complication of cancer and its treatment that can significantly impair quality of life. Although the specific mechanisms remain poorly understood, inflammation is now considered to be a distinct component of CRF in addition to effects of depression, anxiety, insomnia, and other factors. One key biological pathway that may link inflammation and CRF is indoleamine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related cognitive impairment studies
Share to Cancer survivorship and care
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25728366
DOI: 10.1002/cncr.29302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammation‐induced activation of the indoleamine 2,3‐dioxygenase pathway: Relevance to cancer‐related fatiguePMID 25728366Read ↗

Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders: A Systemic ReviewSemantic proximity Read ↗

The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It ComplicatedSemantic proximity Read ↗

Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic PathwaySemantic proximity Read ↗

Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer diseaseSemantic proximity Read ↗

Genomic Variants Associated With Cancer-Related Fatigue: A Systematic ReviewSemantic proximity Read ↗

Targeting the kynurenine pathway: another therapeutic opportunity in the metabolic crosstalk between cancer and immune cellsSemantic proximity Read ↗

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and diseaseSemantic proximity Read ↗

Role of indoleamine 2,3-dioxygenase in health and diseaseSemantic proximity Read ↗

What is the prospect of indoleamine 2,3-dioxygenase 1 inhibition in cancer? Extrapolation from the pastSemantic proximity Read ↗

Targeting the kynurenine pathway in gliomas: Insights into pathogenesis, therapeutic targets, and clinical advancesSemantic proximity Read ↗

The tryptophan–kynurenine pathway in immunomodulation and cancer metastasisSemantic proximity Read ↗

Commonalities in the Features of Cancer and Chronic Fatigue Syndrome (CFS): Evidence for Stress-Induced Phenotype Instability?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.