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Parkinson's Disease rs117896735 Variant Regulates INPP5F Expression in Brain Tissues and Increases Risk of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Xue Feng, Gao Luyan, Chen TingTing, Chen Hongyuan, Zhang Haihua, Wang Tao, Han Zhifa, Gao Shan, Wang Longcai, Hu Yang, Tang Jiangwei, Huang Lei, Liu Guiyou, Zhang Yan

Abstract excerpt

BACKGROUND: Both INPP5D and INPP5F are members of INPP5 family. INPP5F rs117896735 variant was associated with Parkinson's disease (PD) risk, and INPP5D was an Alzheimer's disease (AD) risk gene. However, it remains unclear about the roles of INPP5F rs117896735 variant in AD. OBJECTIVE: We aim to investigate the roles of rs117896735 in AD. METHODS: First, we conducted a candidate variant study to evaluate the...

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PMID: 35848021
DOI: 10.3233/JAD-220086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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