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Article

miR-199a-3p/5p regulate tumorgenesis via targeting Rheb in non-small cell lung cancer.

International journal of biological sciences - 1 Jan 2022

Liu Xiaomin, Wang Xianyi, Chai Binshu, Wu Zong, Gu Zhitao, Zou Heng, Zhang Hui, Li Yanli, Sun Qiangling, Fang Wentao, Ma Zhongliang

Abstract excerpt

Lung cancer is one of the deadliest cancers, in which non-small cell lung cancer (NSCLC) accounting for 85% and has a low survival rate of 5 years. Dysregulation of microRNAs (miRNAs) can participate in tumor regulation and many major diseases. In this study, we found that miR-199a-3p/5p were down-expressed in NSCLC tissue samples, cell lines, and the patient sample database. MiR-199a-3p/5p overexpression could...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35844793
DOI: 10.7150/ijbs.70312
PMCID: PMC9274486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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