Article
Reversible mutations in gliding motility and virulence genes: A flexible and efficient phage defence mechanism in Flavobacterium psychrophilum.
Environmental microbiology - 1 Oct 2022
Jørgensen Jóhanna, Sundell Krister, Castillo Daniel, Dramshøj Liv S, Jørgensen Natasja B, Madsen Susie B, Landor Lotta, Wiklund Tom, Donati Valentina L, Madsen Lone, Dalsgaard Inger, Middelboe Mathias
Abstract excerpt
Flavobacteria are among the most important pathogens in freshwater salmonid aquaculture worldwide. Due to concerns regarding development of antibiotic resistance, phage therapy has been proposed as a solution to decrease pathogen load. However, application of phages is challenged by the development of phage resistance, and knowledge of the mechanisms and implications of phage resistance is therefore required. To...
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